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THE MAIN TENDENCIES OF SOCIAL AND ECONOMIC TRANSFORMATION OF CITIES IN THE TRANS-BAIKAL TERRITORY

In this paper, city-status settlements of the Trans-Baikal Territory are considered. The Trans-Baikal Territory is a territorial entity of the Russian Federation located in the south of Asian part of Russia. Cities of the Trans-Baikal Territory are economic and cultural centres of regions; they play an important role in development and support of the surrounding territory. In this paper, demographic, migration, social and economic conditions of the cities are reviewed. The analysis of conditions in cities has been performed on the basis of statistical data collected from the administrations of the cities of the region and other published statistical materials on the basis of a comparative geographical method, as well as a review of the literature. The generality of tendencies in the social and economic situation and regional peculiarities of cities are shown. In all cities of the region there is a decrease in the population. The paper concludes that, by now, the issue of migration loss is the strategically important development problem in the Trans-Baikal Territory

Rethinking the Roles of Fashion Designers : The Case of Pre Helsinki

Abstract: This paper discusses the diverse roles fashion designers play in the contemporary fashion industry. Taking Finland as a case, it particularly investigates how fashion designers are involved in regional identity formation. By conceptualizing the place-making ability of fashion designers, it adds a new perspective on the expanded roles of fashion designers recognized in design research. This is done through exploration of Pre Helsinki, a platform launched in 2013 seeking to internationalize Finnish fashion. This platform, created and operated mostly by fashion designers, serves as a vivid example of the different roles that designers can play. The study is based on qualitative methods, namely, semi-structured interviews and ethnographic observation. Five characteristics of Pre Helsinki and five fashion designers? corresponding roles were identified, based on thematic analysis of the data. This paper concludes with suggestions for further investigation on fashion designers to establish a dialogue between fashion and design research.Peer reviewe

Sustainable Solutions for Wearable Technologies:Mapping the Product Development Life Cycle

Wearable technologies involve the integration of technology into clothing or accessories to bring new functionalities for people on the move. Many examples of wearables are emerging, from simple fitness tracking watches to electronics deeply embedded into garments for multi-touch sensing and control for personal music players. Without careful development, wearables can have a negative impact on the environment due to increased production of electronic components, increased e-waste from abandoned devices, and increased energy usage. We examine environmental sustainability issues through a review of recent research and cases across three broad areas including the fashion industry, information and communications technology (ICT), and wearable technologies. In the analysis, we examine stages in the product life cycle and identify the unique issues for each sector, including the extraction of materials, production process, distribution of products, use, and disposal of products that have reached the end of their life. The findings are gathered as implications for design so that researchers, educators, designers, developers, and product managers will gain an overview of the issues related to environmental sustainability. Related examples of products and prototypes are provided to enable informed choices during the design and development of wearables that are more environmentally sustainable

Light-induced sulfur transport inside single-walled carbon nanotubes

This article belongs to the Section 2D and Carbon Nanomaterials.Filling of single-walled carbon nanotubes (SWCNTs) and extraction of the encapsulated species from their cavities are perspective treatments for tuning the functional properties of SWCNT-based materials. Here, we have investigated sulfur-modified SWCNTs synthesized by the ampoule method. The morphology and chemical states of carbon and sulfur were analyzed by transmission electron microscopy, Raman scattering, thermogravimetric analysis, X-ray photoelectron and near-edge X-ray absorption fine structure spectroscopies. Successful encapsulation of sulfur inside SWCNTs cavities was demonstrated. The peculiarities of interactions of SWCNTs with encapsulated and external sulfur species were analyzed in details. In particular, the donor–acceptor interaction between encapsulated sulfur and host SWCNT is experimentally demonstrated. The sulfur-filled SWCNTs were continuously irradiated in situ with polychromatic photon beam of high intensity. Comparison of X-ray spectra of the samples before and after the treatment revealed sulfur transport from the interior to the surface of SWCNTs bundles, in particular extraction of sulfur from the SWCNT cavity. These results show that the moderate heating of filled nanotubes could be used to de-encapsulate the guest species tuning the local composition, and hence, the functional properties of SWCNT-based materials.This work was supported by the Russian Science Foundation (Project 18-72-00017), the bilateral Program “Russian-Germany Laboratory at BESSY II” in the part of XPS and C K-edge NEXAFS measurements, and shared research center SSTRC on the basis of the Novosibirsk VEPP-4 - VEPP-2000 complex at BINP SB RAS, using equipment supported by project RFMEFI62119X0022 in the part of S K-edge NEXAFS measurements. R.A. acknowledges the support from the Spanish Ministerio de Economia y Competitividad (MAT2016-79776-P, AEI/FEDER, EU), from the European Union’s Horizon 2020 programme under the project “ESTEEM3” (823717) and from the Government of Aragon and the European Social Fund under the project “Construyendo Europa desde Aragon” 2014–2020 (grant number E13_17R, FEDER, EU).Peer reviewe

Study of cytotoxicity performance of carbon nanohorns by method of spin probes

The effects of as-produced and treated by HNO3(3M) carbon nanohorns on the microviscosity of rat erythrocyte membranes and the viscosity of the water-containing plasma protein matrix were investigated by the method of spin probes. Addition of nanohorns at the concentration of 100 μg/ml to a suspension of erythrocytes led to an increase in membrane microviscosity during 4 h (about 60% effect). In addition, it was shown that nanohorns also induced an increased polarity of the microenvironment for lipophilic probes in the outer layer of membrane phospholipids, as well as disorders in erythrocytes membranes. Addition of nanohorns to plasma led to a little decrease in the viscosity of water and protein matrix, apparently, due to its partial destruction, impacting especially albumin. Pristine and treated by HNO3(3M) acid nanohorns was found more cytotoxic than nanoparticles of oxidized graphene, and significantly less than carbon nanotubes, which are known to dramatically increase the microviscosity of the membranes of erythrocytes and disrupt their integrity

Facilitates Chromatin Transcription Complex Is an “Accelerator” of Tumor Transformation and Potential Marker and Target of Aggressive Cancers

SummaryThe facilitates chromatin transcription (FACT) complex is involved in chromatin remodeling during transcription, replication, and DNA repair. FACT was previously considered to be ubiquitously expressed and not associated with any disease. However, we discovered that FACT is the target of a class of anticancer compounds and is not expressed in normal cells of adult mammalian tissues, except for undifferentiated and stem-like cells. Here, we show that FACT expression is strongly associated with poorly differentiated aggressive cancers with low overall survival. In addition, FACT was found to be upregulated during in vitro transformation and to be necessary, but not sufficient, for driving transformation. FACT also promoted survival and growth of established tumor cells. Genome-wide mapping of chromatin-bound FACT indicated that FACT’s role in cancer most likely involves selective chromatin remodeling of genes that stimulate proliferation, inhibit cell death and differentiation, and regulate cellular stress responses